I was using MalwareBytes AND SuperAntiSpyware AND SpyBot, but with a new update, Malware Bytes started making our computers unusable and slow. So, I deleted Malware and installed Kaspersky. Why do I use so many? Each have found viruses that the others have not. What happens is that my kids want me to get obscure mods on bad websites that have files on them full of viruses, so they ended up on my PC and I basically was the one that allowed them to pass the protection because I installed them. So, 1. I stopped downloading that stuff and 2. I stay protected. 
SpyBot - I don't keep it in memory. I just scan about once a month with it. Superantispyware does a great job of getting rid of adware viruses, but doesn't seem to be able to BLOCK them from happening in the first place.
@Snow

SpyBot - I don't keep it in memory. I just scan about once a month with it. Superantispyware does a great job of getting rid of adware viruses, but doesn't seem to be able to BLOCK them from happening in the first place.
@Snow