I was there on the forums for it in 2012 when there were many who were actively working on making these stones. They were calcinating urine and someone actually finished making the stone after some years of work on it. Someone got sent to the hospital with radiation poisoning after ingesting the "completed" stone. The forum was shut down, I don't know what happened to the other participants. It might be possible to make it work but the risk of failure is pretty high and it takes a long time to make.
Edit;
Here's a thread about it with the author of the book (sign00) answering questions;
Alchemy and The Philosopher's Stone is Real, page 7
www.abovetopsecret.com
And here's an archived link for the forum;