As I said in another thread (and as this guy said in the video, in that other thread), the Universe is big. It's really, really big! It got to contain secrets, mysteries that are just as ... mysterious and secret, as the Universe itself is huge and infinite. I like open questions like that!
Are some things beyond what intelligent life can possibly comprehend, no matter what/when/how? Will those things always be, ultimately unreachable for our minds, or is there a chance that everything can be understood and learned by various means?
I guess the best example would be this: How and why was the universe created? Seriously, unless you can actually talk to the creator himself, who lives outside of the Universe, since he created it (for instance), it's unlikely that you'll ever get an answer. Maybe you can find or get an answer, but you'll never the answer.
Well then, do you believe there are things out there, that we, living beings of what we call the universe, are not meant to know?